Josef Neu

Josef Neu, M.D.

Professor

Department: MD-PEDS-NEONATOLOGY
Business Phone: (352) 273-8985
Business Email: neu@ufl.edu

About Josef Neu

Dr. Neu is Professor, Department of Pediatrics, Division of Neonatology; he received his Bachelor of Arts Degree in 1971, at Wisconsin State University, Whitewater, WI. In 1975 he received his Medical Doctorate, University of Wisconsin, Madison, WI. Dr. Neu completed his Pediatrics Residency at John Hopkins Hospital, Baltimore, MD from 1975-1978, 1978-1980 Postdoctoral Fellow in Neonatology, Stanford University Medical Center, Stanford, CA. In 1987 he completed his Sabbatical, Inselspital, at the University of Bern, Switzerland. 

 Dr. Neu has received during his career several honors and awards. He has chaired National and International Committees. Dr. Neu is active on several Society Membership, Editorial boards, journal reviewer, Service to the Community, Service to schools. He is well known for his lectures here and aboard.

His current research interests include developing an updated taxonomy of intestinal injuries frequently termed necrotizing enterocolitis, precision nutrition using artificial intelligence and multiomics, and is the principal investigator of the Connection Trial, an international prospective randomized trial designed to decrease major morbidities and mortality in preterm infants. He is also the Chairman of the Board of the IPOKRaTES Foundation, involved in global educational activities.

Accomplishments

Avroy Fanaroff Education Award
2024 · American Academy of Pediatrics

Teaching Profile

Courses Taught
2018
MDC7401 Senior Pediatric Clk
2018
MCB7979 Advanced Research
2018
MCB7980 Research for Doctoral Dissertation
2011-2012
HSC4970 Public Health and Health Professions Senior Honors Thesis
2010
HSC4905 Individual Study
2023-2025
BMS6751 Nutrition and Health

Board Certifications

  • Neonatal – Perinatal Medicine
    American Board of Pediatrics

Clinical Profile

Specialties
  • Pediatrics
Subspecialties
  • Neonatal-Perinatal Medicine
Areas of Interest
  • Type 1 diabetes
  • Type 2 diabetes
  • Vision problems

Research Profile

Nutrition and the GI environment in the neonate have major effects not only during infancy, but for the entire lifetime of the individual, and this can even span generations due to epigenetic effects. Our lab has several ongoing projects that involve the requirements for certain amino acids such as glutamine and arginine in very low birthweight infants, the effect of various nutrients on subsequent development of Type 1 and Type 2 diabetes, the effect of the intestinal commensal microflora and probiotics on intestinal development, and the effects of novel nutritional agents on retinal diseases such as retinopathy of prematurity. Our work spans from evaluation of basic mechanisms of nutrients in cell cultures, studies in animal models and translation of these to and from studies in human infants.

Most recent research interests include developing an updated taxonomy of intestinal injuries frequently termed necrotizing enterocolitis, precision nutrition using artificial intelligence and multiomics, and is the principal investigator of the Connection Trial, an international prospective randomized trial designed to decrease major morbidities and mortality in preterm infants.

Areas of Interest
  • Barrier Function of the GI tract
  • Biochemical Nutrition of the Neonate
  • Developmental Gastroenterology
Open Researcher and Contributor ID (ORCID)

0000-0002-6973-0592

Publications

2024
A Scoping Review of the Oral Microbiome in Preterm Infants.
American journal of perinatology. 41(S 01):e2990-e3002 [DOI] 10.1055/s-0043-1776344. [PMID] 37907200.
2024
An expert panel on the adequacy of safety data and physiological roles of dietary bovine osteopontin in infancy.
Frontiers in nutrition. 11 [DOI] 10.3389/fnut.2024.1404303. [PMID] 38919388.
2024
Antibiotics Use and Its Effects on the Establishment of Feeding Tolerance in Preterm Neonates.
American journal of perinatology. 41(S 01):e2248-e2253 [DOI] 10.1055/a-2108-1960. [PMID] 37308133.
2024
Clinical Characteristics of Necrotizing Enterocolitis Diagnosed by Independent Adjudication of Abdominal Radiographs, Laparotomy, or Autopsy in Preterm Infants in the “Connection Trial”.
American journal of perinatology. [DOI] 10.1055/s-0044-1788275. [PMID] 38986486.
2024
COVID-19 booster enhances IgG mediated viral neutralization by human milk in vitro.
Frontiers in nutrition. 11 [DOI] 10.3389/fnut.2024.1289413. [PMID] 38406184.
2024
Effect of Routine Gastric Residual Aspiration on the Preterm Infant Fecal Microbiome.
American journal of perinatology. 41(S 01):e212-e220 [DOI] 10.1055/a-1877-6306. [PMID] 35709728.
2024
Increased antibiotic resistance in preterm neonates under early antibiotic use.
mSphere. [DOI] 10.1128/msphere.00286-24. [PMID] 39373498.
2024
Progression of Enteral Feeding Volumes in Extremely Low Birth Weight Infants in the “Connection Trial”.
American journal of perinatology. 41(S 01):e2717-e2726 [DOI] 10.1055/s-0043-1774314. [PMID] 37683670.
2024
Reassessing acquired neonatal intestinal diseases using unsupervised machine learning.
Pediatric research. 96(1):165-171 [DOI] 10.1038/s41390-024-03074-x. [PMID] 38413766.
2024
Struggling to Understand the NEC Spectrum—Could the Integration of Metabolomics, Clinical-Laboratory Data, and Other Emerging Technologies Help Diagnosis?
Metabolites. 14(10) [DOI] 10.3390/metabo14100521. [PMID] 39452903.
2024
The conundrum of intestinal injury in preterm infants receiving mother’s own milk
Journal of Perinatology. [DOI] 10.1038/s41372-024-02125-9.
2024
The evolution of personalized nutrition
Nature Medicine. 30(7):1826-1827 [DOI] 10.1038/s41591-024-03000-y.
2024
When Biological Causality Is Determined in a Court of Law.
JAMA pediatrics. [DOI] 10.1001/jamapediatrics.2024.4012. [PMID] 39374031.
2023
Application of Artificial Intelligence in the Early Detection of Retinopathy of Prematurity: Review of the Literature.
Neonatology. 120(5):558-565 [DOI] 10.1159/000531441. [PMID] 37490881.
2023
Association between early life antibiotic exposure and development of early childhood atopic dermatitis
JAAD International. 10:68-74 [DOI] 10.1016/j.jdin.2022.11.002. [PMID] 36688099.
2023
Detection of SARS-CoV-2 IgA and IgG in human milk and breastfeeding infant stool 6 months after maternal COVID-19 vaccination.
Journal of perinatology : official journal of the California Perinatal Association. 43(6):775-781 [DOI] 10.1038/s41372-022-01581-5. [PMID] 36631564.
2023
Editorial response to Cosentino and Marino RE: detection of SARS-CoV-2 IgA and IgG in human milk and breastfeeding infant stool 6 months after maternal COVID-19 vaccination.
Journal of perinatology : official journal of the California Perinatal Association. 43(6):828-829 [DOI] 10.1038/s41372-023-01660-1. [PMID] 37024528.
2023
Editorial: Microbiome in the first 1000 days: multi-omic interactions, physiological effects, and clinical implications.
Frontiers in cellular and infection microbiology. 13 [DOI] 10.3389/fcimb.2023.1242626. [PMID] 37457954.
2023
Monitoring and management of hypertriglyceridemia in extremely low birth weight neonates receiving intravenous lipid emulsions: A national survey.
Early human development. 186 [DOI] 10.1016/j.earlhumdev.2023.105872. [PMID] 37862901.
2023
Multiomic Investigations into Lung Health and Disease
Microorganisms. 11(8) [DOI] 10.3390/microorganisms11082116. [PMID] 37630676.
2023
Multiomics, artificial intelligence, and precision medicine in perinatology.
Pediatric research. 93(2):308-315 [DOI] 10.1038/s41390-022-02181-x. [PMID] 35804156.
2023
Skin microbiome sampling in the preterm neonate.
Pediatric dermatology. 40(1):129-131 [DOI] 10.1111/pde.15158. [PMID] 36385397.
2023
Summary of the Joint National Institutes of Health and the Food and Drug Administration Workshop Titled “Exploring the Science Surrounding the Safe Use of Bioactive Ingredients in Infant Formula: Considerations for an Assessment Framework”.
The Journal of pediatrics. 255:30-41.e1 [DOI] 10.1016/j.jpeds.2022.11.027. [PMID] 36463938.
2023
Untargeted Metabolomic Analysis of Lactation-Stage-Matched Human and Bovine Milk Samples at 2 Weeks Postnatal.
Nutrients. 15(17) [DOI] 10.3390/nu15173768. [PMID] 37686800.
2022
[El microbioma como objetivo terapéutico en la nutrición de prematuros].
World review of nutrition and dietetics. 122:193-204 [DOI] 10.1159/000526515. [PMID] 36174514.
2022
[Enterocolitis necrotizante].
World review of nutrition and dietetics. 122:395-407 [DOI] 10.1159/000526554. [PMID] 36174528.
2022
Assessing the safety of bioactive ingredients in infant formula that affect the immune system: recommendations from an expert panel.
The American journal of clinical nutrition. 115(2):570-587 [DOI] 10.1093/ajcn/nqab346. [PMID] 34634105.
2022
Association between atopic dermatitis and race from infancy to early childhood: a retrospective cohort study.
International journal of dermatology. 61(6):727-732 [DOI] 10.1111/ijd.15805. [PMID] 34378189.
2022
Detection of SARS-CoV-2 IgA and IgG in human milk and breastfeeding infant stool 6 months after maternal COVID-19 vaccination.
Research square. [DOI] 10.21203/rs.3.rs-1950944/v1. [PMID] 36032985.
2022
Development of the Gastrointestinal Tract in Newborns as a Challenge for an Appropriate Nutrition: A Narrative Review
Nutrients. 14(7) [DOI] 10.3390/nu14071405. [PMID] 35406018.
2022
Gastrointestinal and feeding issues for infants
Seminars in perinatology. 46(1) [DOI] 10.1016/j.semperi.2021.151546. [PMID] 34920883.
2022
Integrating longitudinal clinical and microbiome data to predict growth faltering in preterm infants.
Journal of biomedical informatics. 128 [DOI] 10.1016/j.jbi.2022.104031. [PMID] 35183765.
2022
Neonatal Feeding Tube Colonization and the Potential Effect on Infant Health: A Review.
Frontiers in nutrition. 9 [DOI] 10.3389/fnut.2022.775014. [PMID] 35284460.
2022
Neonatal sepsis and the skin microbiome.
Journal of perinatology : official journal of the California Perinatal Association. 42(11):1429-1433 [DOI] 10.1038/s41372-022-01451-0. [PMID] 35817842.
2022
Prevention of Necrotizing Enterocolitis.
Clinics in perinatology. 49(1):195-206 [DOI] 10.1016/j.clp.2021.11.012. [PMID] 35210001.
2022
Tachygastria in Preterm Infants: A Longitudinal Cohort Study.
Journal of pediatric gastroenterology and nutrition. 75(5):564-571 [DOI] 10.1097/MPG.0000000000003575. [PMID] 36305880.
2021
Antibiotics and the developing intestinal microbiome, metabolome and inflammatory environment in a randomized trial of preterm infants.
Scientific reports. 11(1) [DOI] 10.1038/s41598-021-80982-6. [PMID] 33479274.
2021
Detection of SARS-CoV-2-Specific IgA in the Human Milk of COVID-19 Vaccinated Lactating Health Care Workers.
Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine. 16(12):1004-1009 [DOI] 10.1089/bfm.2021.0122. [PMID] 34427487.
2021
Duration of neonatal intensive care unit exposure associated with decreased risk of atopic dermatitis.
Pediatric dermatology. 38(1):83-87 [DOI] 10.1111/pde.14405. [PMID] 33063877.
2021
Frozen Mother’s Own Milk Can Be Used Effectively to Personalize Donor Human Milk.
Frontiers in microbiology. 12 [DOI] 10.3389/fmicb.2021.656889. [PMID] 33936012.
2021
Implications of the vaginal microbiome and potential restorative strategies on maternal health: a narrative review.
Journal of perinatal medicine. 49(4):402-411 [DOI] 10.1515/jpm-2020-0367. [PMID] 33554571.
2021
Introduction.
Seminars in perinatology. 45(6) [DOI] 10.1016/j.semperi.2021.151448. [PMID] 34247836.
2021
Maternal microbial factors that affect the fetus and subsequent offspring.
Seminars in perinatology. 45(6) [DOI] 10.1016/j.semperi.2021.151449. [PMID] 34266675.
2021
Necrotizing Enterocolitis.
World review of nutrition and dietetics. 122:367-378 [DOI] 10.1159/000514760. [PMID] 34352768.
2021
Perspectives of pregnant and breastfeeding women on longitudinal clinical studies that require non-invasive biospecimen collection – a qualitative study.
BMC pregnancy and childbirth. 21(1) [DOI] 10.1186/s12884-021-03541-x. [PMID] 33472584.
2021
Routine Early Antibiotic Use in SymptOmatic Preterm Neonates: A Pilot Randomized Controlled Trial.
The Journal of pediatrics. 229:294-298.e3 [DOI] 10.1016/j.jpeds.2020.09.056. [PMID] 32979383.
2021
The Microbiome as a Therapeutic Target in Preterm Nutrition.
World review of nutrition and dietetics. 122:180-190 [DOI] 10.1159/000514737. [PMID] 34352753.
2021
Using machine learning analysis to assist in differentiating between necrotizing enterocolitis and spontaneous intestinal perforation: A novel predictive analytic tool
Journal of Pediatric Surgery. 56(10):1703-1710 [DOI] 10.1016/j.jpedsurg.2020.11.008.
2020
A Qualitative Study of Pregnant Women’s Perspectives on Antibiotic Use for Mom and Child: Implications for Developing Tailored Health Education Interventions
Antibiotics. 9(10) [DOI] 10.3390/antibiotics9100704. [PMID] 33076539.
2020
An Overview of Systematic Reviews of Randomized-Controlled Trials for Preventing Necrotizing Enterocolitis in Preterm Infants.
Neonatology. 117(1):46-56 [DOI] 10.1159/000504371. [PMID] 31838477.
2020
Antibiotics Effects on the Fecal Metabolome in Preterm Infants
Metabolites. 10(8) [DOI] 10.3390/metabo10080331. [PMID] 32823682.
2020
Assessment of Neonatal Intensive Care Unit Practices and Preterm Newborn Gut Microbiota and 2-Year Neurodevelopmental Outcomes.
JAMA network open. 3(9) [DOI] 10.1001/jamanetworkopen.2020.18119. [PMID] 32965499.
2020
Effect of Aspiration and Evaluation of Gastric Residuals on Intestinal Inflammation, Bleeding, and Gastrointestinal Peptide Level.
The Journal of pediatrics. 217:165-171.e2 [DOI] 10.1016/j.jpeds.2019.10.036. [PMID] 31757473.
2020
Gut Injury and the Microbiome in Neonates.
Clinics in perinatology. 47(2):369-382 [DOI] 10.1016/j.clp.2020.02.010. [PMID] 32439117.
2020
Gut microbiota maturation during early human life induces enterocyte proliferation via microbial metabolites.
BMC microbiology. 20(1) [DOI] 10.1186/s12866-020-01892-7. [PMID] 32652929.
2020
Gut Microbiota, Host Gene Expression, and Cell Traffic via Milk.
Nestle Nutrition Institute workshop series. 94:94-102 [DOI] 10.1159/000504996. [PMID] 32203958.
2020
Metabolomic Profile of Personalized Donor Human Milk
Molecules. 25(24) [DOI] 10.3390/molecules25245783. [PMID] 33302441.
2020
Necrotizing Enterocolitis: A Multi-omic Approach and the Role of the Microbiome.
Digestive diseases and sciences. 65(3):789-796 [DOI] 10.1007/s10620-020-06104-w. [PMID] 32008132.
2020
Necrotizing Enterocolitis: The Future.
Neonatology. 117(2):240-244 [DOI] 10.1159/000506866. [PMID] 32155645.
2020
Postnatal pediatric systemic antibiotic episodes during the first three years of life are not associated with mode of delivery.
PloS one. 15(3) [DOI] 10.1371/journal.pone.0229861. [PMID] 32130278.
2020
Preterm neonatal immunology at the intestinal interface.
Cellular and molecular life sciences : CMLS. 77(7):1209-1227 [DOI] 10.1007/s00018-019-03316-w. [PMID] 31576423.
2019
Consumption of Mother’s Own Milk by Infants Born Extremely Preterm Following Implementation of a Donor Human Milk Program: A Retrospective Cohort Study.
The Journal of pediatrics. 211:33-38 [DOI] 10.1016/j.jpeds.2019.03.040. [PMID] 31060805.
2019
Effect of Gastric Residual Evaluation on Enteral Intake in Extremely Preterm Infants: A Randomized Clinical Trial.
JAMA pediatrics. 173(6):534-543 [DOI] 10.1001/jamapediatrics.2019.0800. [PMID] 31034045.
2019
Fueling the Optimal Microbiome: Interventions for Severe Acute Malnutrition.
Cell host & microbe. 26(3):307-308 [DOI] 10.1016/j.chom.2019.08.015. [PMID] 31513768.
2019
Initial microbial community of the neonatal stomach immediately after birth.
Gut microbes. 10(3):289-297 [DOI] 10.1080/19490976.2018.1520578. [PMID] 30404568.
2019
Microbial Colonization Coordinates the Pathogenesis of a Klebsiella pneumoniae Infant Isolate.
Scientific reports. 9(1) [DOI] 10.1038/s41598-019-39887-8. [PMID] 30833613.
2019
Mother’s Own Milk: How Does It Differ from Donor Milk for the Baby.
Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine. 14(S1):S3-S4 [DOI] 10.1089/bfm.2019.0036. [PMID] 30985206.
2019
Multiomics-based strategies for taming intestinal inflammation in the neonate.
Current opinion in clinical nutrition and metabolic care. 22(3):217-222 [DOI] 10.1097/MCO.0000000000000559. [PMID] 30883466.
2019
Necrotizing Enterocolitis: Long Term Complications.
Current pediatric reviews. 15(2):115-124 [DOI] 10.2174/1573396315666190312093119. [PMID] 30864508.
2019
Pathophysiology of Necrotizing Enterocolitis: An Update.
Current pediatric reviews. 15(2):68-87 [DOI] 10.2174/1573396314666181102123030. [PMID] 30387398.
2019
The infantile cutaneous microbiome: A review.
Pediatric dermatology. 36(5):574-580 [DOI] 10.1111/pde.13870. [PMID] 31332846.
2018
Electrogastrography, Near-infrared Spectroscopy, and Acoustics to Measure Gastrointestinal Development in Preterm Babies.
Journal of pediatric gastroenterology and nutrition. 66(6):e146-e152 [DOI] 10.1097/MPG.0000000000001867. [PMID] 29287010.
2018
Enteral Arg-Gln Dipeptide Administration Increases Retinal Docosahexaenoic Acid and Neuroprotectin D1 in a Murine Model of Retinopathy of Prematurity.
Investigative ophthalmology & visual science. 59(2):858-869 [DOI] 10.1167/iovs.17-23034. [PMID] 29490339.
2018
Enteral Feeding as an Adjunct to Hypothermia in Neonates with Hypoxic-Ischemic Encephalopathy.
Neonatology. 113(4):347-352 [DOI] 10.1159/000487848. [PMID] 29510382.
2018
Food Protein-Induced Enterocolitis Instead of Necrotizing Enterocolitis? A Neonatal Intensive Care Unit Case Series.
The Journal of pediatrics. 200:270-273 [DOI] 10.1016/j.jpeds.2018.04.048. [PMID] 29803301.
2018
Gastrointestinal Development: Implications for Management of Preterm and Term Infants.
Gastroenterology clinics of North America. 47(4):773-791 [DOI] 10.1016/j.gtc.2018.07.005. [PMID] 30337032.
2018
Maternal milk feedings reduce sepsis, necrotizing enterocolitis and improve outcomes of premature infants.
Journal of perinatology : official journal of the California Perinatal Association. 38(1):71-74 [DOI] 10.1038/jp.2017.149. [PMID] 29048409.
2018
Necrotizing enterocolitis comes in different forms: Historical perspectives and defining the disease.
Seminars in fetal & neonatal medicine. 23(6):370-373 [DOI] 10.1016/j.siny.2018.07.004. [PMID] 30100524.
2018
Necrotizing enterocolitis.
Seminars in fetal & neonatal medicine. 23(6) [DOI] 10.1016/j.siny.2018.08.009. [PMID] 30279063.
2018
Necrotizing enterocolitis: The intestinal microbiome, metabolome and inflammatory mediators.
Seminars in fetal & neonatal medicine. 23(6):400-405 [DOI] 10.1016/j.siny.2018.08.001. [PMID] 30172660.
2018
The Neonatal Microbiome and Its Partial Role in Mediating the Association between Birth by Cesarean Section and Adverse Pediatric Outcomes.
Neonatology. 114(2):103-111 [DOI] 10.1159/000487102. [PMID] 29788027.
2017
Commensal Propionibacterium strain UF1 mitigates intestinal inflammation via Th17 cell regulation
The Journal Of Clinical Investigation. 127(11):3970-3986 [DOI] 10.1172/JCI95376. [PMID] 28945202.
2017
Dysbiosis in the Neonatal Period: Role of Cesarean Section.
Nestle Nutrition Institute workshop series. 88:57-66 [DOI] 10.1159/000455215. [PMID] 28346935.
2017
Epigenetic Matters: The Link between Early Nutrition, Microbiome, and Long-term Health Development.
Frontiers in pediatrics. 5 [DOI] 10.3389/fped.2017.00178. [PMID] 28879172.
2017
Necrotizing Enterocolitis and Human Milk Feeding: A Systematic Review.
Clinics in perinatology. 44(1):49-67 [DOI] 10.1016/j.clp.2016.11.009. [PMID] 28159209.
2017
Nutritional strategies and gut microbiota composition as risk factors for necrotizing enterocolitis in very-preterm infants.
The American journal of clinical nutrition. 106(3):821-830 [DOI] 10.3945/ajcn.117.152967. [PMID] 28659297.
2017
Pathogenesis of NEC: Impact of an altered intestinal microbiome.
Seminars in perinatology. 41(1):29-35 [DOI] 10.1053/j.semperi.2016.09.015. [PMID] 27986328.
2017
Personalization of the Microbiota of Donor Human Milk with Mother’s Own Milk.
Frontiers in microbiology. 8 [DOI] 10.3389/fmicb.2017.01470. [PMID] 28824595.
2017
Post-hypoxia Invasion of the fetal brain by multidrug resistant Staphylococcus.
Scientific reports. 7(1) [DOI] 10.1038/s41598-017-06789-6. [PMID] 28743956.
2017
Potential Nutrients for Preventing or Treating Bronchopulmonary Dysplasia.
Paediatric respiratory reviews. 22:83-88 [DOI] 10.1016/j.prrv.2016.08.013. [PMID] 27843119.
2017
Probiotics in Newborns and Children.
Pediatric clinics of North America. 64(6):1271-1289 [DOI] 10.1016/j.pcl.2017.08.006. [PMID] 29173785.
2017
What Are Optimal Cesarean Section Rates in the U.S. and How Do We Get There? A Review of Evidence-Based Recommendations and Interventions.
Journal of women's health (2002). 26(12):1285-1291 [DOI] 10.1089/jwh.2016.6188. [PMID] 28825512.
2016
Intestinal Microbiota Studies in Preterm Infants.
Journal of pediatric gastroenterology and nutrition. 62(2):193-4 [DOI] 10.1097/MPG.0000000000001068. [PMID] 26655942.
2016
The human gut microbiota in perinatology and neonatology.
Seminars in fetal & neonatal medicine. 21(6) [DOI] 10.1016/j.siny.2016.06.004. [PMID] 27522308.
2016
The microbiome during pregnancy and early postnatal life.
Seminars in fetal & neonatal medicine. 21(6):373-379 [DOI] 10.1016/j.siny.2016.05.001. [PMID] 27286643.
2016
Working group reports: evaluation of the evidence to support practice guidelines for nutritional care of preterm infants-the Pre-B Project.
The American journal of clinical nutrition. 103(2):648S-78S [DOI] 10.3945/ajcn.115.117309. [PMID] 26791182.
2015
Aspiration and evaluation of gastric residuals in the neonatal intensive care unit: state of the science.
The Journal of perinatal & neonatal nursing. 29(1):51-9; quiz E2 [DOI] 10.1097/JPN.0000000000000080. [PMID] 25633400.
2015
Developmental aspects of maternal-fetal, and infant gut microbiota and implications for long-term health.
Maternal health, neonatology and perinatology. 1 [DOI] 10.1186/s40748-015-0007-4. [PMID] 27057323.
2015
Early factors leading to later obesity: interactions of the microbiome, epigenome, and nutrition.
Current problems in pediatric and adolescent health care. 45(5):134-42 [DOI] 10.1016/j.cppeds.2015.03.003. [PMID] 26043042.
2015
Factors influencing gastrointestinal tract and microbiota immune interaction in preterm infants.
Pediatric research. 77(6):726-31 [DOI] 10.1038/pr.2015.54. [PMID] 25760550.
2015
Preterm infant nutrition, gut bacteria, and necrotizing enterocolitis.
Current opinion in clinical nutrition and metabolic care. 18(3):285-8 [DOI] 10.1097/MCO.0000000000000169. [PMID] 25807349.
2015
Reply–Gastric residuals, feeding intolerance, and nectrotizing enterocolitis in preterm infants.
Pediatrics and neonatology. 56(2):138-9 [DOI] 10.1016/j.pedneo.2014.10.007. [PMID] 25623004.
2015
The value of routine evaluation of gastric residuals in very low birth weight infants.
Journal of perinatology : official journal of the California Perinatal Association. 35(1):57-60 [DOI] 10.1038/jp.2014.147. [PMID] 25166623.
2014
Decoding the enigma of necrotizing enterocolitis in premature infants.
Pathophysiology : the official journal of the International Society for Pathophysiology. 21(1):21-7 [DOI] 10.1016/j.pathophys.2013.11.011. [PMID] 24373685.
2014
Gastric residual evaluation in preterm neonates: a useful monitoring technique or a hindrance?
Pediatrics and neonatology. 55(5):335-40 [DOI] 10.1016/j.pedneo.2014.02.008. [PMID] 25129325.
2014
Manipulation of the intestinal microbiome in newborn infants.
Advances in nutrition (Bethesda, Md.). 5(1):114-8 [DOI] 10.3945/an.113.004820. [PMID] 24425730.
2014
Meconium microbiome analysis identifies bacteria correlated with premature birth.
PloS one. 9(3) [DOI] 10.1371/journal.pone.0090784. [PMID] 24614698.
2014
Necrotizing enterocolitis.
World review of nutrition and dietetics. 110:253-63 [DOI] 10.1159/000358474. [PMID] 24751635.
2014
Necrotizing enterocolitis: the mystery goes on.
Neonatology. 106(4):289-95 [DOI] 10.1159/000365130. [PMID] 25171544.
2014
Packed red blood cell transfusion is not associated with increased risk of necrotizing enterocolitis in premature infants.
Journal of perinatology : official journal of the California Perinatal Association. 34(11):858-62 [DOI] 10.1038/jp.2014.59. [PMID] 25144159.
2014
Probiotics and necrotizing enterocolitis.
Clinics in perinatology. 41(4):967-78 [DOI] 10.1016/j.clp.2014.08.014. [PMID] 25459784.
2014
The developing intestinal microbiome: probiotics and prebiotics.
World review of nutrition and dietetics. 110:167-76 [DOI] 10.1159/000358465. [PMID] 24751628.
2014
The Infant Intestinal Microbiome: Friend Or Foe (Vol 86, Pg S67, 2010)
Early Human Development. 90(3):163-164 [DOI] 10.1016/j.earlhumdev.2013.12.004.
2014
The time for a confirmative necrotizing enterocolitis probiotics prevention trial in the extremely low birth weight infant in North America is now!
The Journal of pediatrics. 165(2):389-94 [DOI] 10.1016/j.jpeds.2014.05.012. [PMID] 24948349.
2013
A Pocock approach to sequential meta-analysis of clinical trials.
Research synthesis methods. 4(3):269-79 [DOI] 10.1002/jrsm.1088. [PMID] 24348752.
2013
Distortions in development of intestinal microbiota associated with late onset sepsis in preterm infants.
PloS one. 8(1) [DOI] 10.1371/journal.pone.0052876. [PMID] 23341915.
2013
Effect of intestinal microbial ecology on the developing brain.
JAMA pediatrics. 167(4):374-9 [DOI] 10.1001/jamapediatrics.2013.497. [PMID] 23400224.
2013
Feeding the preterm infant: opportunities and challenges of bringing science to the bedside.
The Journal of pediatrics. 162(3 Suppl):S101-6 [DOI] 10.1016/j.jpeds.2012.11.059. [PMID] 23445840.
2013
Gastrointestinal function development and microbiota.
Italian journal of pediatrics. 39 [DOI] 10.1186/1824-7288-39-15. [PMID] 23433508.
2013
Glutamine supplementation in neonates: is there a future?
Nestle Nutrition Institute workshop series. 77:47-56 [DOI] 10.1159/000351383. [PMID] 24107495.
2013
Intestinal microbial ecology and environmental factors affecting necrotizing enterocolitis.
PloS one. 8(12) [DOI] 10.1371/journal.pone.0083304. [PMID] 24386174.
2013
Intestinal mucosal defense system, Part 1. Consensus recommendations for immunonutrients.
The Journal of pediatrics. 162(3 Suppl):S56-63 [DOI] 10.1016/j.jpeds.2012.11.054. [PMID] 23445849.
2013
Intestinal mucosal defense system, Part 2. Probiotics and prebiotics.
The Journal of pediatrics. 162(3 Suppl):S64-71 [DOI] 10.1016/j.jpeds.2012.11.055. [PMID] 23445850.
2013
Neonatal Necrotizing Enterocolitis
World Review of Nutrition and Dietetics. 107:122-127 [DOI] 10.1159/000345739.
2013
Nutrition support of neonatal patients at risk for necrotizing enterocolitis: response to Fallon et al (2012).
JPEN. Journal of parenteral and enteral nutrition. 37(1) [DOI] 10.1177/0148607112459358. [PMID] 22972878.
2013
Pilot study using proteomics to identify predictive biomarkers of necrotizing enterocolitis from buccal swabs in very low birth weight infants.
Neonatology. 104(3):234-42 [DOI] 10.1159/000353721. [PMID] 24030199.
2013
The altered gut microbiome and necrotizing enterocolitis.
Clinics in perinatology. 40(1):93-108 [DOI] 10.1016/j.clp.2012.12.009. [PMID] 23415266.
2013
The Microbiome and Its Impact on Disease in the Preterm Patient.
Current pediatrics reports. 1(4):215-221 [PMID] 25422793.
2012
Arginyl-glutamine dipeptide or docosahexaenoic acid attenuate hyperoxia-induced lung injury in neonatal mice.
Nutrition (Burbank, Los Angeles County, Calif.). 28(11-12):1186-91 [DOI] 10.1016/j.nut.2012.04.001. [PMID] 23044165.
2012
Arginyl-glutamine dipeptide or docosahexaenoic acid attenuates hyperoxia-induced small intestinal injury in neonatal mice.
Journal of pediatric gastroenterology and nutrition. 54(4):499-504 [DOI] 10.1097/MPG.0b013e3182330867. [PMID] 22020559.
2012
Baby and breast: a dynamic interaction.
Pediatric research. 71(2) [DOI] 10.1038/pr.2011.35. [PMID] 22258122.
2012
Buccal Swab Il-1Ra in Necrotizing Enterocolitis: a Predictive Biomarker
The FASEB's Journal. 26
2012
Gut microbiota correlates with energy gain from dietary fibre and appears to be associated with acute and chronic intestinal diseases.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 18 Suppl 4:62-6 [DOI] 10.1111/j.1469-0691.2012.03859.x. [PMID] 22647053.
2012
Lactation and neonatal nutrition: defining and refining the critical questions.
Journal of mammary gland biology and neoplasia. 17(2):167-88 [DOI] 10.1007/s10911-012-9261-5. [PMID] 22752723.
2012
Microbial cell components induced tolerance to flagellin-stimulated inflammation through Toll-like receptor pathways in intestinal epithelial cells.
Cytokine. 60(3):806-11 [DOI] 10.1016/j.cyto.2012.08.003. [PMID] 22944462.
2012
Recent developments in necrotizing enterocolitis.
JPEN. Journal of parenteral and enteral nutrition. 36(1 Suppl):30S-5S [DOI] 10.1177/0148607111422068. [PMID] 22237874.
2012
Systems Biology Approach in Pathway Analysis of Low Dose Flagellin Induced Tolerance To Flagellin-Stimulated Inflammation in Caco-2 Cells
The FASEB's Journal. 26
2011
Cesarean versus vaginal delivery: long-term infant outcomes and the hygiene hypothesis.
Clinics in perinatology. 38(2):321-31 [DOI] 10.1016/j.clp.2011.03.008. [PMID] 21645799.
2011
Early postnatal nutrition and programming of the preterm neonate.
Nutrition reviews. 69(2):76-82 [DOI] 10.1111/j.1753-4887.2010.00370.x. [PMID] 21294741.
2011
Fecal microbiota in premature infants prior to necrotizing enterocolitis.
PloS one. 6(6) [DOI] 10.1371/journal.pone.0020647. [PMID] 21674011.
2011
Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes.
PloS one. 6(10) [DOI] 10.1371/journal.pone.0025792. [PMID] 22043294.
2011
Inhibition of type 1 diabetes correlated to a Lactobacillus johnsonii N6.2-mediated Th17 bias.
Journal of immunology (Baltimore, Md. : 1950). 186(6):3538-46 [DOI] 10.4049/jimmunol.1001864. [PMID] 21317395.
2011
Ischemia-reperfusion and neonatal intestinal injury.
The Journal of pediatrics. 158(2 Suppl):e25-8 [DOI] 10.1016/j.jpeds.2010.11.009. [PMID] 21238702.
2011
Long-term effects of neonatal glutamine-enriched nutrition in very-low-birth-weight infants.
Nutrition reviews. 69(1):2-8 [DOI] 10.1111/j.1753-4887.2010.00359.x. [PMID] 21198630.
2011
Necrotizing enterocolitis.
The New England journal of medicine. 364(3):255-64 [DOI] 10.1056/NEJMra1005408. [PMID] 21247316.
2011
NIH Consensus Development Conference statement: inhaled nitric-oxide therapy for premature infants.
Pediatrics. 127(2):363-9 [DOI] 10.1542/peds.2010-3507. [PMID] 21220405.
2011
Probiotics for pregnant women and preterm neonates.
The American journal of clinical nutrition. 93(1):3-4 [DOI] 10.3945/ajcn.110.006346. [PMID] 21123464.
2011
Routine probiotics for premature infants: let’s be careful!
The Journal of pediatrics. 158(4):672-4 [DOI] 10.1016/j.jpeds.2010.11.028. [PMID] 21220142.
2011
The developing intestinal microbiome and its relationship to health and disease in the neonate.
Journal of perinatology : official journal of the California Perinatal Association. 31 Suppl 1:S29-34 [DOI] 10.1038/jp.2010.172. [PMID] 21448201.
2011
The intestinal microbiome of infants and the use of probiotics.
Current opinion in pediatrics. 23(2):145-50 [DOI] 10.1097/MOP.0b013e3283444ccb. [PMID] 21415831.
2011
Toward defining the autoimmune microbiome for type 1 diabetes.
The ISME journal. 5(1):82-91 [DOI] 10.1038/ismej.2010.92. [PMID] 20613793.
2010
Butyrate and type 1 diabetes mellitus: can we fix the intestinal leak?
Journal of pediatric gastroenterology and nutrition. 51(4):414-7 [DOI] 10.1097/MPG.0b013e3181dd913a. [PMID] 20706153.
2010
Enteral Nutrient Supply for Preterm Infants: Commentary From the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition Committee On Nutrition
Journal of Pediatric Gastroenterology and Nutrition. 50(1):85-91 [DOI] 10.1097/MPG.0b013e3181adaee0. [PMID] 19881390.
2010
Intestinal microbial ecology in premature infants assessed with non-culture-based techniques.
The Journal of pediatrics. 156(1):20-5 [DOI] 10.1016/j.jpeds.2009.06.063. [PMID] 19783002.
2010
Lactobacillus johnsonii N6.2 mitigates the development of type 1 diabetes in BB-DP rats.
PloS one. 5(5) [DOI] 10.1371/journal.pone.0010507. [PMID] 20463897.
2010
Maternal Separation in the Neonatal Period Decreases Adipose Gr and 11 Beta Hsd Mrna in the Adult Rat
Journal of Investigative Medicine. 58
2010
Molecular modulation of intestinal epithelial barrier: contribution of microbiota.
Journal of biomedicine & biotechnology. 2010 [DOI] 10.1155/2010/305879. [PMID] 20150966.
2010
Monitoring technologies in the neonatal intensive care unit: implications for the detection of necrotizing enterocolitis.
Journal of perinatology : official journal of the California Perinatal Association. 30(11):701-8 [DOI] 10.1038/jp.2010.9. [PMID] 20336080.
2010
NIH consensus development conference: Inhaled nitric oxide therapy for premature infants.
NIH consensus and state-of-the-science statements. 27(5):1-34 [PMID] 21042341.
2010
Nonadministration of routine probiotics unethical–really?
Pediatrics. 126(3):e740-1; author reply e743 [DOI] 10.1542/peds.2010-1949A. [PMID] 20810713.
2010
The infant intestinal microbiome: friend or foe?
Early human development. 86 Suppl 1(Suppl 1):67-71 [DOI] 10.1016/j.earlhumdev.2010.01.018. [PMID] 20116944.
2010
The intestinal microbiome: relationship to type 1 diabetes.
Endocrinology and metabolism clinics of North America. 39(3):563-71 [DOI] 10.1016/j.ecl.2010.05.008. [PMID] 20723820.
2009
50 Years Ago in the Journal of Pediatrics Lactic Acid Milk in the Feeding of Premature Infants
Journal of Pediatrics. 154(6) [DOI] 10.1016/j.jpeds.2008.11.054.
2009
Biomarkers for infants at risk for necrotizing enterocolitis: clues to prevention?
Pediatric research. 65(5 Pt 2):91R-97R [DOI] 10.1203/PDR.0b013e31819dba7d. [PMID] 19190533.
2009
Culture-independent identification of gut bacteria correlated with the onset of diabetes in a rat model.
The ISME journal. 3(5):536-48 [DOI] 10.1038/ismej.2009.5. [PMID] 19225551.
2009
Glutamine deprivation alters intestinal tight junctions via a PI3-K/Akt mediated pathway in Caco-2 cells.
The Journal of nutrition. 139(4):710-4 [DOI] 10.3945/jn.108.101485. [PMID] 19211824.
2009
Influence of fecal sample storage on bacterial community diversity.
The open microbiology journal. 3:40-6 [DOI] 10.2174/1874285800903010040. [PMID] 19440250.
2009
Is it time to stop starving premature infants?
Journal of perinatology : official journal of the California Perinatal Association. 29(6):399-400 [DOI] 10.1038/jp.2009.46. [PMID] 19474815.
2009
Live and heat-killed Lactobacillus rhamnosus GG: effects on proinflammatory and anti-inflammatory cytokines/chemokines in gastrostomy-fed infant rats.
Pediatric research. 66(2):203-7 [DOI] 10.1203/PDR.0b013e3181aabd4f. [PMID] 19390478.
2009
Metabolic effects of different protein intakes after short term undernutrition in artificially reared infant rats.
Early human development. 85(1):41-9 [DOI] 10.1016/j.earlhumdev.2008.06.009. [PMID] 18650036.
2009
Potential of Immunomodulatory Agents for Prevention and Treatment of Neonatal Sepsis
Journal of Perinatology. 29(2):79-88 [DOI] 10.1038/jp.2008.132. [PMID] 18769381.
2009
Potential roles and clinical utility of prebiotics in newborns, infants, and children: proceedings from a global prebiotic summit meeting, New York City, June 27-28, 2008.
The Journal of pediatrics. 155(5):S61-70 [DOI] 10.1016/j.jpeds.2009.08.022. [PMID] 19840609.
2009
Probiotic microbes: do they need to be alive to be beneficial?
Nutrition reviews. 67(9):546-50 [DOI] 10.1111/j.1753-4887.2009.00226.x. [PMID] 19703261.
2009
Probiotics and prevention of necrotizing enterocolitis.
Early human development. 85(10 Suppl):S71-4 [DOI] 10.1016/j.earlhumdev.2009.08.021. [PMID] 19781874.
2009
Resident duty hour restrictions: is less really more?
The Journal of pediatrics. 154(5):631-632.e1 [DOI] 10.1016/j.jpeds.2009.02.004. [PMID] 19364553.
2009
Use of nutrition to prevent stress-induced immunosuppression in the pediatric intensive care unit: a clinical trials minefield.
JPEN. Journal of parenteral and enteral nutrition. 33(4):440-1 [DOI] 10.1177/0148607108328521. [PMID] 19407104.
2008
A roadmap for understanding and preventing necrotizing enterocolitis.
Current gastroenterology reports. 10(5):450-7 [PMID] 18799119.
2008
Intestinal microbiota development in the premature neonate: establishment of a lasting commensal relationship?
Nutrition reviews. 66(11):658-63 [DOI] 10.1111/j.1753-4887.2008.00119.x. [PMID] 19019028.
2008
Live and ultraviolet-inactivated Lactobacillus rhamnosus GG decrease flagellin-induced interleukin-8 production in Caco-2 cells.
The Journal of nutrition. 138(11):2264-8 [DOI] 10.3945/jn.108.093658. [PMID] 18936229.
2008
Neonatal formula feeding leads to immunological alterations in an animal model of type 1 diabetes.
Pediatric research. 63(3):303-7 [PMID] 18091354.
2008
The “perfect storm” for type 1 diabetes: the complex interplay between intestinal microbiota, gut permeability, and mucosal immunity.
Diabetes. 57(10):2555-62 [DOI] 10.2337/db08-0331. [PMID] 18820210.
2008
The Intestinal Microbiome: Friend Or Foe?
Neonatology. 94:230-231
2007
Arginine supplementation for neonatal necrotizing enterocolitis: are we ready?
The British journal of nutrition. 97(5):814-5 [PMID] 17408520.
2007
Gastrointestinal development and meeting the nutritional needs of premature infants.
The American journal of clinical nutrition. 85(2):629S-634S [PMID] 17284768.
2007
Gastrointestinal maturation and implications for infant feeding.
Early human development. 83(12):767-75 [PMID] 17913404.
2007
Microbes and the developing gastrointestinal tract.
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. 22(2):174-82 [PMID] 17374791.
2007
Pathophysiology of glutamine and glutamate metabolism in premature infants.
Current opinion in clinical nutrition and metabolic care. 10(1):75-9 [PMID] 17143059.
2007
Perinatal and neonatal manipulation of the intestinal microbiome: a note of caution.
Nutrition reviews. 65(6 Pt 1):282-5 [PMID] 17605304.
2007
Postnatal nutrition and adult health programming.
Seminars in fetal & neonatal medicine. 12(1):78-86 [PMID] 17157087.
2006
Gastrointestinal maturation and feeding.
Seminars in perinatology. 30(2):77-80 [PMID] 16731281.
2006
Lactobacillus rhamnosus GG decreases lipopolysaccharide-induced systemic inflammation in a gastrostomy-fed infant rat model.
Journal of pediatric gastroenterology and nutrition. 42(5):545-52 [PMID] 16707979.
2006
NICHD: AAP workshop on neonatology research and training areas of research in neonatal gastroenterology.
Journal of perinatology : official journal of the California Perinatal Association. 26 Suppl 2:S19-22 [PMID] 16801963.
2006
The dipeptide Arg-Gln inhibits retinal neovascularization in the mouse model of oxygen-induced retinopathy.
Investigative ophthalmology & visual science. 47(7):3151-5 [PMID] 16799062.
2005
Alive and dead Lactobacillus rhamnosus GG decrease tumor necrosis factor-alpha-induced interleukin-8 production in Caco-2 cells.
The Journal of nutrition. 135(7):1752-6 [PMID] 15987860.
2005
Changes in intestinal morphology and permeability in the biobreeding rat before the onset of type 1 diabetes.
Journal of pediatric gastroenterology and nutrition. 40(5):589-95 [PMID] 15861021.
2005
Feeding intolerance in very-low-birthweight infants: what is it and what can we do about it?
Acta paediatrica (Oslo, Norway : 1992). Supplement. 94(449):93-9 [PMID] 16214773.
2005
Glutamine modulates LPS-induced IL-8 production through IkappaB/NF-kappaB in human fetal and adult intestinal epithelium.
The Journal of nutrition. 135(2):245-51 [PMID] 15671221.
2005
Intestinal innate immunity: how does it relate to the pathogenesis of necrotizing enterocolitis.
Seminars in pediatric surgery. 14(3):137-44 [PMID] 16084400.
2005
Neonatal necrotizing enterocolitis: an update.
Acta paediatrica (Oslo, Norway : 1992). Supplement. 94(449):100-5 [PMID] 16214774.
2005
Probiotics: protecting the intestinal ecosystem?
The Journal of pediatrics. 147(2):143-6 [PMID] 16126038.
2005
The ‘myth’ of asphyxia and hypoxia-ischemia as primary causes of necrotizing enterocolitis.
Biology of the neonate. 87(2):97-8 [PMID] 15528876.
2005
The developing intestinal ecosystem: implications for the neonate.
Pediatric research. 58(4):625-8 [PMID] 16189184.
2004
Artificial rearing of mouse pups: development of a mouse pup in a cup model.
Pediatric research. 56(2):250-5 [PMID] 15181197.
2004
Effects of protein deprivation on growth and small intestine morphology are not improved by glutamine or glutamate in gastrostomy-fed rat pups.
Journal of pediatric gastroenterology and nutrition. 39(1):28-33 [PMID] 15187776.
2004
Glutamine decreases lipopolysaccharide-induced intestinal inflammation in infant rats.
American journal of physiology. Gastrointestinal and liver physiology. 286(6):G914-21 [PMID] 14726310.
2004
Glutamine regulates Caco-2 cell tight junction proteins.
American journal of physiology. Gastrointestinal and liver physiology. 287(3):G726-33 [PMID] 15130874.
2004
Mechanism of glutamine-mediated amelioration of lipopolysaccharide-induced IL-8 production in Caco-2 cells.
Cytokine. 26(2):57-65 [PMID] 15050605.
2004
Substitutes for glutamine in proliferation of rat intestinal epithelial cells.
Nutrition (Burbank, Los Angeles County, Calif.). 20(3):292-7 [PMID] 14990271.
2003
Enteral glutamine supplementation and morbidity in low birth weight infants.
The Journal of pediatrics. 142(6):662-8 [PMID] 12838195.
2003
Glutamine and barrier function in cultured Caco-2 epithelial cell monolayers.
The Journal of nutrition. 133(7):2176-9 [PMID] 12840174.
2003
Glutamine decreases lipopolysaccharide-induced IL-8 production in Caco-2 cells through a non-NF-kappaB p50 mechanism.
Cytokine. 22(3-4):77-83 [PMID] 12849706.
2003
Glutamine supplements in premature infants: why and how.
Journal of pediatric gastroenterology and nutrition. 37(5):533-5 [PMID] 14581791.
2003
Glutamine supports recovery from loss of transepithelial resistance and increase of permeability induced by media change in Caco-2 cells.
The Journal of nutritional biochemistry. 14(7):401-8 [PMID] 12915221.
2003
Immunonutrients and neonates.
European journal of pediatrics. 162(3):122-128 [DOI] 10.1007/s00431-002-1128-0. [PMID] 12655412.
2003
Nutrition in the neonatal intensive care unit: how do we reduce the incidence of extrauterine growth restriction?
Journal of perinatology : official journal of the California Perinatal Association. 23(4):337-44 [PMID] 12774145.
2003
Nutrition of premature and critically ill neonates.
Nestle Nutrition workshop series. Clinical & performance programme. 8:171-81; discussion 181 [PMID] 12968454.
2002
Arginine supplementation and the prevention of necrotizing enterocolitis in very low birth weight infants.
The Journal of pediatrics. 140(4):389-91 [PMID] 12006949.
2002
Glutamine metabolism in the fetus and critically ill low birth weight neonate.
Advances in pediatrics. 49:203-26 [PMID] 12214772.
2002
Glutamine supplementation and deprivation: effect on artificially reared rat small intestinal morphology.
Pediatric research. 52(3):430-6 [PMID] 12193680.
2002
Glutamine: clinical applications and mechanisms of action.
Current opinion in clinical nutrition and metabolic care. 5(1):69-75 [PMID] 11790953.
2002
Indomethacin, dexamethasone, and intestinal damage in infant rats.
Journal of pediatric gastroenterology and nutrition. 35(2):154-61 [PMID] 12187290.
2002
Update on host defense and immunonutrients.
Clinics in perinatology. 29(1):41-64 [PMID] 11917739.
2001
Glutamine in the fetus and critically ill low birth weight neonate: metabolism and mechanism of action.
The Journal of nutrition. 131(9 Suppl):2585S-9S; discussion 2590S [DOI] 10.1093/jn/131.9.2585S. [PMID] 11533317.
1999
Glutamine supplementation in low-birth-weight infants: mechanisms of action.
JPEN. Journal of parenteral and enteral nutrition. 23(5 Suppl):S49-51 [PMID] 10483895.
1999
Glutamine synthetase: a key enzyme for intestinal epithelial differentiation?
JPEN. Journal of parenteral and enteral nutrition. 23(3):140-6 [PMID] 10338221.
1999
Inhibition of glutamine synthetase decreases proliferation of cultured rat intestinal epithelial cells.
The Journal of nutrition. 129(1):57-62 [PMID] 9915876.
1999
Necrotizing enterocolitis: pathophysiology and prevention.
JPEN. Journal of parenteral and enteral nutrition. 23(5 Suppl):S13-7 [PMID] 10483886.
1998
Enteral glutamine supplementation for very-low-birth-weight infants decreases hospital costs.
JPEN. Journal of parenteral and enteral nutrition. 22(6):352-6 [PMID] 9829607.
1997
Characterization of glutamine synthetase transcript, protein, and enzyme activity in the human placenta.
Placenta. 18(7):541-5 [PMID] 9290149.
1997
Enteral glutamine supplementation for very low birth weight infants decreases morbidity.
The Journal of pediatrics. 131(5):691-9 [PMID] 9403648.
1997
Glutamine metabolism in very low birth weight infants.
Pediatric research. 41(3):391-6 [PMID] 9078541.
1996
Characterization of glutaminase in the developing rat small intestine.
The Journal of nutrition. 126(4 Suppl):1121S-30S [DOI] 10.1093/jn/126.suppl_4.1121S. [PMID] 8642444.
1996
Enteral glutamine supplementation for the very low birthweight infant: plasma amino acid concentrations.
The Journal of nutrition. 126(4 Suppl):1115S-20S [DOI] 10.1093/jn/126.suppl_4.1115S. [PMID] 8642443.
1996
Glutamine nutrition and metabolism: where do we go from here ?
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 10(8):829-37 [PMID] 8666159.
1996
Necrotizing enterocolitis: the search for a unifying pathogenic theory leading to prevention.
Pediatric clinics of North America. 43(2):409-32 [PMID] 8614608.
1996
Nutrient absorption in the preterm neonate.
Clinics in perinatology. 23(2):229-43 [PMID] 8780903.
1996
Ontogeny of glutamine synthetase in rat small intestine.
Pediatric research. 39(4 Pt 1):643-8 [PMID] 8848339.
1995
Localization of rat small intestine glutamine synthetase using immunofluorescence and in situ hybridization.
JPEN. Journal of parenteral and enteral nutrition. 19(3):179-81 [PMID] 8551643.
1993
Meconium passage in very-low-birth-weight infants.
JPEN. Journal of parenteral and enteral nutrition. 17(6):537-40 [PMID] 8301808.
1993
Ontogeny of small intestinal glutaminase and glutamine synthetase in the rat: response to dexamethasone.
Biology of the neonate. 64(6):368-75 [PMID] 7904483.
1992
Gastrointestinal priming prior to full enteral nutrition in very low birth weight infants.
Journal of pediatric gastroenterology and nutrition. 15(2):163-70 [PMID] 1403464.
1992
The role of dietary cholesterol in infants.
Comprehensive therapy. 18(10):35-7 [PMID] 1458816.
1991
Effect of cholesterol deprivation on piglet small intestine and serum lipids.
Journal of pediatric gastroenterology and nutrition. 12(4):494-500 [PMID] 1865285.
1990
Ontogeny of prostaglandin E1 receptor binding in rat small intestine.
Prostaglandins, leukotrienes, and essential fatty acids. 41(1):63-6 [PMID] 2174566.
1990
Scientifically-based strategies for nutrition of the high-risk low birth weight infant.
European journal of pediatrics. 150(1):2-13 [PMID] 2127745.
1989
Changes in phospholipid and cholesterol concentrations of the rat microvillus membrane during maturation.
Journal of pediatric gastroenterology and nutrition. 9(1):89-93 [PMID] 2674384.
1989
Determination of extracellular fluid volume using impedance measurements.
Critical care medicine. 17(4):360-3 [PMID] 2702844.
1989
Factors associated with age of onset of necrotizing enterocolitis.
American journal of perinatology. 6(4):455-60 [PMID] 2789545.
1989
Functional development of the fetal gastrointestinal tract.
Seminars in perinatology. 13(3):224-35 [PMID] 2665101.
1989
Localization and characterization of prostaglandin E1 receptors in rat small intestine.
Prostaglandins, leukotrienes, and essential fatty acids. 36(3):129-34 [PMID] 2550964.
1988
Prostaglandin concentrations in human milk.
The American journal of clinical nutrition. 47(4):649-52 [PMID] 3162635.
1987
Alterations in piglet small intestine after cholesterol deprivation.
Pediatric research. 22(3):330-4 [PMID] 3116496.

Grants

Sep 2023 – Aug 2024
Machine learning and Multiomics for Predictive Models and Biomarker Discovery in Preterm Infants
Role: Principal Investigator
Funding: BAYLOR COLLEGE OF MEDICINE via NATL INST OF HLTH
Jul 2023 ACTIVE
Frequent Standardized Oral Care Using Human Milk to Reduce Oral Dysbiosis and Improve Health Outcomes in Preterm Very Low Birth Weight Infants
Role: Co-Investigator
Funding: GERBER FOUNDATION
Jan 2022 – Jan 2024
Human milk antibody response to COVID-19 vaccination and protection to breastfeeding infants
Role: Other
Funding: GERBER FOUNDATION
Dec 2019 ACTIVE
A randomized, double blind, parallel-group, placebo controlled study to evaluate the efficacy and safety of IBP-9414 in premature infants 500-1500g birth weight in the prevention of necrotizing enterocolitis The Connection study
Role: Principal Investigator
Funding: INFANT BACTERIAL THERAPEUTICS AB
Aug 2018 – May 2023
Optimal Feeding Tube Dwell Time in VLBW to Reduce Feeding Tube Contamination
Role: Co-Investigator
Funding: NATL INST OF HLTH NINR
Dec 2016 – Nov 2019
Antibiotic Effects on the Developing Microbiome Metabolome and Morbidites in Preterm Neonates.
Role: Principal Investigator
Funding: NATL INST OF HLTH NICHD
Mar 2016 – Mar 2019
A RANDOMIZED DOUBLE BLIND PARALLEL GROUP DOSE ESCALATION PLACEBO CONTROLLED MULTICENTER STUDY TO INVESTIGATE THE…..
Role: Principal Investigator
Funding: PREMIER RESEARCH INTERNATIONAL via INFANT BACTERIAL THERAPEUTICS AB
Oct 2015 – Sep 2024
Coordinating Investigator Clinical Trial IBP-9414 and clinical expert services
Role: Principal Investigator
Funding: INFANT BACTERIAL THERAPEUTICS AB
Sep 2015 – Sep 2018
Refaunation of Donor Human Milk with Mother's Own Milk
Role: Principal Investigator
Funding: MEDELA AG
Mar 2013 – Jan 2018
Routine Aspiration of Residual Gastric Contents in Very Low Birth Weight Infants
Role: Project Manager
Funding: NATL INST OF HLTH NINR

Education

Fellowship – Neonatal – Perinatal Medicine
1980 · Stanford University
Residency – Pediatrics
1978 · John's Hopkins University
Medical Degree
1975 · University of Wisconsin

Contact Details

Phones:
Business:
(352) 273-8985
Emails:
Business:
neu@ufl.edu
Addresses:
Business Mailing:
PO Box 100296
GAINESVILLE FL 32610
Business Street:
HD 112 JHMHC
GAINESVILLE FL 32611