Josef Neu, M.D.
Professor
About Josef Neu
Dr. Neu is Professor, Department of Pediatrics, Division of Neonatology; he received his Bachelor of Arts Degree in 1971, at Wisconsin State University, Whitewater, WI. In 1975 he received his Medical Doctorate, University of Wisconsin, Madison, WI. Dr. Neu completed his Pediatrics Residency at John Hopkins Hospital, Baltimore, MD from 1975-1978, 1978-1980 Postdoctoral Fellow in Neonatology, Stanford University Medical Center, Stanford, CA. In 1987 he completed his Sabbatical, Inselspital, at the University of Bern, Switzerland.
Dr. Neu has received during his career several honors and awards. He has chaired National and International Committees. Dr. Neu is active on several Society Membership, Editorial boards, journal reviewer, Service to the Community, Service to schools. He is well known for his lectures here and aboard.
His current research interests include developing an updated taxonomy of intestinal injuries frequently termed necrotizing enterocolitis, precision nutrition using artificial intelligence and multiomics, and is the principal investigator of the Connection Trial, an international prospective randomized trial designed to decrease major morbidities and mortality in preterm infants. He is also the Chairman of the Board of the IPOKRaTES Foundation, involved in global educational activities.
Accomplishments
Avroy Fanaroff Education Award
2024
·
American Academy of Pediatrics
Teaching Profile
Courses Taught
2018
MDC7401 Senior Pediatric Clk
2018
MCB7979 Advanced Research
2018
MCB7980 Research for Doctoral Dissertation
2011-2012
HSC4970 Public Health and Health Professions Senior Honors Thesis
2010
HSC4905 Individual Study
2023-2024
BMS6751 Nutrition and Health
Board Certifications
-
Neonatal – Perinatal MedicineAmerican Board of Pediatrics
Clinical Profile
Specialties
- Pediatrics
Subspecialties
- Neonatal-Perinatal Medicine
Areas of Interest
- Pediatric Intestinal Rehabilitation Program
- Type 1 Diabetes
- Type 2 Diabetes
- Vision problems
Research Profile
Nutrition and the GI environment in the neonate have major effects not only during infancy, but for the entire lifetime of the individual, and this can even span generations due to epigenetic effects. Our lab has several ongoing projects that involve the requirements for certain amino acids such as glutamine and arginine in very low birthweight infants, the effect of various nutrients on subsequent development of Type 1 and Type 2 diabetes, the effect of the intestinal commensal microflora and probiotics on intestinal development, and the effects of novel nutritional agents on retinal diseases such as retinopathy of prematurity. Our work spans from evaluation of basic mechanisms of nutrients in cell cultures, studies in animal models and translation of these to and from studies in human infants.
Most recent research interests include developing an updated taxonomy of intestinal injuries frequently termed necrotizing enterocolitis, precision nutrition using artificial intelligence and multiomics, and is the principal investigator of the Connection Trial, an international prospective randomized trial designed to decrease major morbidities and mortality in preterm infants.
Areas of Interest
- Barrier Function of the GI tract
- Biochemical Nutrition of the Neonate
- Developmental Gastroenterology
Publications
Academic Articles
2025
Clinical Characteristics of Necrotizing Enterocolitis Diagnosed by Independent Adjudication of Abdominal Radiographs, Laparotomy, or Autopsy in Preterm Infants in the “Connection Trial”.
American journal of perinatology.
42(2):268-280
[DOI] 10.1055/s-0044-1788275.
[PMID] 38986486.
2025
Digital twins, synthetic patient data, and in-silico trials: can they empower paediatric clinical trials?
The Lancet. Digital health.
[DOI] 10.1016/j.landig.2025.01.007.
[PMID] 40360351.
2025
Gastrointestinal (GI)-lung-brain axis.
Seminars in fetal & neonatal medicine.
[DOI] 10.1016/j.siny.2025.101639.
[PMID] 40222850.
2025
Neonatal microbiome in the multiomics era: development and its impact on long-term health.
Pediatric research.
[DOI] 10.1038/s41390-025-03953-x.
[PMID] 40021924.
2025
Quantification and comparison of anti-AAV9 and anti-AAVrh74 antibodies in plasma and human milk: Implications for AAV-based gene therapy candidacy
Journal of Neuromuscular Diseases.
[DOI] 10.1177/22143602251324857.
[PMID] 40207793.
2025
Sex-Related Nutritional Outcomes Among Preterm Very Low Birth-Weight Infants.
Advances in neonatal care : official journal of the National Association of Neonatal Nurses.
25(2):181-187
[DOI] 10.1097/ANC.0000000000001233.
[PMID] 40053867.
2024
A Scoping Review of the Oral Microbiome in Preterm Infants.
American journal of perinatology.
41(S 01):e2990-e3002
[DOI] 10.1055/s-0043-1776344.
[PMID] 37907200.
2024
An expert panel on the adequacy of safety data and physiological roles of dietary bovine osteopontin in infancy.
Frontiers in nutrition.
11
[DOI] 10.3389/fnut.2024.1404303.
[PMID] 38919388.
2024
Antibiotics Use and Its Effects on the Establishment of Feeding Tolerance in Preterm Neonates.
American journal of perinatology.
41(S 01):e2248-e2253
[DOI] 10.1055/a-2108-1960.
[PMID] 37308133.
2024
COVID-19 booster enhances IgG mediated viral neutralization by human milk in vitro.
Frontiers in nutrition.
11
[DOI] 10.3389/fnut.2024.1289413.
[PMID] 38406184.
2024
Effect of Routine Gastric Residual Aspiration on the Preterm Infant Fecal Microbiome.
American journal of perinatology.
41(S 01):e212-e220
[DOI] 10.1055/a-1877-6306.
[PMID] 35709728.
2024
Increased antibiotic resistance in preterm neonates under early antibiotic use.
mSphere.
9(10)
[DOI] 10.1128/msphere.00286-24.
[PMID] 39373498.
2024
Nutrition for the Sick Preterm: Can We Make It More Precise?
Nestle Nutrition Institute workshop series.
100:71-80
[DOI] 10.1159/000540137.
[PMID] 39586266.
2024
Progression of Enteral Feeding Volumes in Extremely Low Birth Weight Infants in the “Connection Trial”.
American journal of perinatology.
41(S 01):e2717-e2726
[DOI] 10.1055/s-0043-1774314.
[PMID] 37683670.
2024
Reassessing acquired neonatal intestinal diseases using unsupervised machine learning.
Pediatric research.
96(1):165-171
[DOI] 10.1038/s41390-024-03074-x.
[PMID] 38413766.
2024
Struggling to Understand the NEC Spectrum—Could the Integration of Metabolomics, Clinical-Laboratory Data, and Other Emerging Technologies Help Diagnosis?
Metabolites.
14(10)
[DOI] 10.3390/metabo14100521.
[PMID] 39452903.
2024
The conundrum of intestinal injury in preterm infants receiving mother’s own milk
Journal of Perinatology.
[DOI] 10.1038/s41372-024-02125-9.
2024
The evolution of personalized nutrition
Nature Medicine.
30(7):1826-1827
[DOI] 10.1038/s41591-024-03000-y.
2024
When Biological Causality Is Determined in a Court of Law.
JAMA pediatrics.
178(12):1239-1240
[DOI] 10.1001/jamapediatrics.2024.4012.
[PMID] 39374031.
2023
Application of Artificial Intelligence in the Early Detection of Retinopathy of Prematurity: Review of the Literature.
Neonatology.
120(5):558-565
[DOI] 10.1159/000531441.
[PMID] 37490881.
2023
Association between early life antibiotic exposure and development of early childhood atopic dermatitis
JAAD International.
10:68-74
[DOI] 10.1016/j.jdin.2022.11.002.
[PMID] 36688099.
2023
Detection of SARS-CoV-2 IgA and IgG in human milk and breastfeeding infant stool 6 months after maternal COVID-19 vaccination.
Journal of perinatology : official journal of the California Perinatal Association.
43(6):775-781
[DOI] 10.1038/s41372-022-01581-5.
[PMID] 36631564.
2023
Editorial response to Cosentino and Marino RE: detection of SARS-CoV-2 IgA and IgG in human milk and breastfeeding infant stool 6 months after maternal COVID-19 vaccination.
Journal of perinatology : official journal of the California Perinatal Association.
43(6):828-829
[DOI] 10.1038/s41372-023-01660-1.
[PMID] 37024528.
2023
Editorial: Microbiome in the first 1000 days: multi-omic interactions, physiological effects, and clinical implications.
Frontiers in cellular and infection microbiology.
13
[DOI] 10.3389/fcimb.2023.1242626.
[PMID] 37457954.
2023
Monitoring and management of hypertriglyceridemia in extremely low birth weight neonates receiving intravenous lipid emulsions: A national survey.
Early human development.
186
[DOI] 10.1016/j.earlhumdev.2023.105872.
[PMID] 37862901.
2023
Multiomic Investigations into Lung Health and Disease
Microorganisms.
11(8)
[DOI] 10.3390/microorganisms11082116.
[PMID] 37630676.
2023
Multiomics, artificial intelligence, and precision medicine in perinatology.
Pediatric research.
93(2):308-315
[DOI] 10.1038/s41390-022-02181-x.
[PMID] 35804156.
2023
Skin microbiome sampling in the preterm neonate.
Pediatric dermatology.
40(1):129-131
[DOI] 10.1111/pde.15158.
[PMID] 36385397.
2023
Summary of the Joint National Institutes of Health and the Food and Drug Administration Workshop Titled “Exploring the Science Surrounding the Safe Use of Bioactive Ingredients in Infant Formula: Considerations for an Assessment Framework”.
The Journal of pediatrics.
255:30-41.e1
[DOI] 10.1016/j.jpeds.2022.11.027.
[PMID] 36463938.
2023
Untargeted Metabolomic Analysis of Lactation-Stage-Matched Human and Bovine Milk Samples at 2 Weeks Postnatal.
Nutrients.
15(17)
[DOI] 10.3390/nu15173768.
[PMID] 37686800.
2022
[El microbioma como objetivo terapéutico en la nutrición de prematuros].
World review of nutrition and dietetics.
122:193-204
[DOI] 10.1159/000526515.
[PMID] 36174514.
2022
[Enterocolitis necrotizante].
World review of nutrition and dietetics.
122:395-407
[DOI] 10.1159/000526554.
[PMID] 36174528.
2022
Assessing the safety of bioactive ingredients in infant formula that affect the immune system: recommendations from an expert panel.
The American journal of clinical nutrition.
115(2):570-587
[DOI] 10.1093/ajcn/nqab346.
[PMID] 34634105.
2022
Association between atopic dermatitis and race from infancy to early childhood: a retrospective cohort study.
International journal of dermatology.
61(6):727-732
[DOI] 10.1111/ijd.15805.
[PMID] 34378189.
2022
Detection of SARS-CoV-2 IgA and IgG in human milk and breastfeeding infant stool 6 months after maternal COVID-19 vaccination.
Research square.
[DOI] 10.21203/rs.3.rs-1950944/v1.
[PMID] 36032985.
2022
Development of the Gastrointestinal Tract in Newborns as a Challenge for an Appropriate Nutrition: A Narrative Review
Nutrients.
14(7)
[DOI] 10.3390/nu14071405.
[PMID] 35406018.
2022
Gastrointestinal and feeding issues for infants
Seminars in perinatology.
46(1)
[DOI] 10.1016/j.semperi.2021.151546.
[PMID] 34920883.
2022
Integrating longitudinal clinical and microbiome data to predict growth faltering in preterm infants.
Journal of biomedical informatics.
128
[DOI] 10.1016/j.jbi.2022.104031.
[PMID] 35183765.
2022
Neonatal Feeding Tube Colonization and the Potential Effect on Infant Health: A Review.
Frontiers in nutrition.
9
[DOI] 10.3389/fnut.2022.775014.
[PMID] 35284460.
2022
Neonatal sepsis and the skin microbiome.
Journal of perinatology : official journal of the California Perinatal Association.
42(11):1429-1433
[DOI] 10.1038/s41372-022-01451-0.
[PMID] 35817842.
2022
Prevention of Necrotizing Enterocolitis.
Clinics in perinatology.
49(1):195-206
[DOI] 10.1016/j.clp.2021.11.012.
[PMID] 35210001.
2022
Tachygastria in Preterm Infants: A Longitudinal Cohort Study.
Journal of pediatric gastroenterology and nutrition.
75(5):564-571
[DOI] 10.1097/MPG.0000000000003575.
[PMID] 36305880.
2021
Antibiotics and the developing intestinal microbiome, metabolome and inflammatory environment in a randomized trial of preterm infants.
Scientific reports.
11(1)
[DOI] 10.1038/s41598-021-80982-6.
[PMID] 33479274.
2021
Detection of SARS-CoV-2-Specific IgA in the Human Milk of COVID-19 Vaccinated Lactating Health Care Workers.
Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine.
16(12):1004-1009
[DOI] 10.1089/bfm.2021.0122.
[PMID] 34427487.
2021
Duration of neonatal intensive care unit exposure associated with decreased risk of atopic dermatitis.
Pediatric dermatology.
38(1):83-87
[DOI] 10.1111/pde.14405.
[PMID] 33063877.
2021
Frozen Mother’s Own Milk Can Be Used Effectively to Personalize Donor Human Milk.
Frontiers in microbiology.
12
[DOI] 10.3389/fmicb.2021.656889.
[PMID] 33936012.
2021
Implications of the vaginal microbiome and potential restorative strategies on maternal health: a narrative review.
Journal of perinatal medicine.
49(4):402-411
[DOI] 10.1515/jpm-2020-0367.
[PMID] 33554571.
2021
Introduction.
Seminars in perinatology.
45(6)
[DOI] 10.1016/j.semperi.2021.151448.
[PMID] 34247836.
2021
Maternal microbial factors that affect the fetus and subsequent offspring.
Seminars in perinatology.
45(6)
[DOI] 10.1016/j.semperi.2021.151449.
[PMID] 34266675.
2021
Necrotizing Enterocolitis.
World review of nutrition and dietetics.
122:367-378
[DOI] 10.1159/000514760.
[PMID] 34352768.
2021
Perspectives of pregnant and breastfeeding women on longitudinal clinical studies that require non-invasive biospecimen collection – a qualitative study.
BMC pregnancy and childbirth.
21(1)
[DOI] 10.1186/s12884-021-03541-x.
[PMID] 33472584.
2021
Routine Early Antibiotic Use in SymptOmatic Preterm Neonates: A Pilot Randomized Controlled Trial.
The Journal of pediatrics.
229:294-298.e3
[DOI] 10.1016/j.jpeds.2020.09.056.
[PMID] 32979383.
2021
The Microbiome as a Therapeutic Target in Preterm Nutrition.
World review of nutrition and dietetics.
122:180-190
[DOI] 10.1159/000514737.
[PMID] 34352753.
2021
Using machine learning analysis to assist in differentiating between necrotizing enterocolitis and spontaneous intestinal perforation: A novel predictive analytic tool.
Journal of pediatric surgery.
56(10):1703-1710
[DOI] 10.1016/j.jpedsurg.2020.11.008.
[PMID] 33342603.
2020
A Qualitative Study of Pregnant Women’s Perspectives on Antibiotic Use for Mom and Child: Implications for Developing Tailored Health Education Interventions
Antibiotics.
9(10)
[DOI] 10.3390/antibiotics9100704.
[PMID] 33076539.
2020
An Overview of Systematic Reviews of Randomized-Controlled Trials for Preventing Necrotizing Enterocolitis in Preterm Infants.
Neonatology.
117(1):46-56
[DOI] 10.1159/000504371.
[PMID] 31838477.
2020
Antibiotics Effects on the Fecal Metabolome in Preterm Infants
Metabolites.
10(8)
[DOI] 10.3390/metabo10080331.
[PMID] 32823682.
2020
Assessment of Neonatal Intensive Care Unit Practices and Preterm Newborn Gut Microbiota and 2-Year Neurodevelopmental Outcomes.
JAMA network open.
3(9)
[DOI] 10.1001/jamanetworkopen.2020.18119.
[PMID] 32965499.
2020
Effect of Aspiration and Evaluation of Gastric Residuals on Intestinal Inflammation, Bleeding, and Gastrointestinal Peptide Level.
The Journal of pediatrics.
217:165-171.e2
[DOI] 10.1016/j.jpeds.2019.10.036.
[PMID] 31757473.
2020
Gut Injury and the Microbiome in Neonates.
Clinics in perinatology.
47(2):369-382
[DOI] 10.1016/j.clp.2020.02.010.
[PMID] 32439117.
2020
Gut microbiota maturation during early human life induces enterocyte proliferation via microbial metabolites.
BMC microbiology.
20(1)
[DOI] 10.1186/s12866-020-01892-7.
[PMID] 32652929.
2020
Gut Microbiota, Host Gene Expression, and Cell Traffic via Milk.
Nestle Nutrition Institute workshop series.
94:94-102
[DOI] 10.1159/000504996.
[PMID] 32203958.
2020
Metabolomic Profile of Personalized Donor Human Milk
Molecules.
25(24)
[DOI] 10.3390/molecules25245783.
[PMID] 33302441.
2020
Necrotizing Enterocolitis: A Multi-omic Approach and the Role of the Microbiome.
Digestive diseases and sciences.
65(3):789-796
[DOI] 10.1007/s10620-020-06104-w.
[PMID] 32008132.
2020
Necrotizing Enterocolitis: The Future.
Neonatology.
117(2):240-244
[DOI] 10.1159/000506866.
[PMID] 32155645.
2020
Postnatal pediatric systemic antibiotic episodes during the first three years of life are not associated with mode of delivery.
PloS one.
15(3)
[DOI] 10.1371/journal.pone.0229861.
[PMID] 32130278.
2020
Preterm neonatal immunology at the intestinal interface.
Cellular and molecular life sciences : CMLS.
77(7):1209-1227
[DOI] 10.1007/s00018-019-03316-w.
[PMID] 31576423.
2019
Consumption of Mother’s Own Milk by Infants Born Extremely Preterm Following Implementation of a Donor Human Milk Program: A Retrospective Cohort Study.
The Journal of pediatrics.
211:33-38
[DOI] 10.1016/j.jpeds.2019.03.040.
[PMID] 31060805.
2019
Effect of Gastric Residual Evaluation on Enteral Intake in Extremely Preterm Infants: A Randomized Clinical Trial.
JAMA pediatrics.
173(6):534-543
[DOI] 10.1001/jamapediatrics.2019.0800.
[PMID] 31034045.
2019
Fueling the Optimal Microbiome: Interventions for Severe Acute Malnutrition.
Cell host & microbe.
26(3):307-308
[DOI] 10.1016/j.chom.2019.08.015.
[PMID] 31513768.
2019
Initial microbial community of the neonatal stomach immediately after birth.
Gut microbes.
10(3):289-297
[DOI] 10.1080/19490976.2018.1520578.
[PMID] 30404568.
2019
Microbial Colonization Coordinates the Pathogenesis of a Klebsiella pneumoniae Infant Isolate.
Scientific reports.
9(1)
[DOI] 10.1038/s41598-019-39887-8.
[PMID] 30833613.
2019
Mother’s Own Milk: How Does It Differ from Donor Milk for the Baby.
Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine.
14(S1):S3-S4
[DOI] 10.1089/bfm.2019.0036.
[PMID] 30985206.
2019
Multiomics-based strategies for taming intestinal inflammation in the neonate.
Current opinion in clinical nutrition and metabolic care.
22(3):217-222
[DOI] 10.1097/MCO.0000000000000559.
[PMID] 30883466.
2019
Necrotizing Enterocolitis: Long Term Complications.
Current pediatric reviews.
15(2):115-124
[DOI] 10.2174/1573396315666190312093119.
[PMID] 30864508.
2019
Pathophysiology of Necrotizing Enterocolitis: An Update.
Current pediatric reviews.
15(2):68-87
[DOI] 10.2174/1573396314666181102123030.
[PMID] 30387398.
2019
The infantile cutaneous microbiome: A review.
Pediatric dermatology.
36(5):574-580
[DOI] 10.1111/pde.13870.
[PMID] 31332846.
2018
Electrogastrography, Near-infrared Spectroscopy, and Acoustics to Measure Gastrointestinal Development in Preterm Babies.
Journal of pediatric gastroenterology and nutrition.
66(6):e146-e152
[DOI] 10.1097/MPG.0000000000001867.
[PMID] 29287010.
2018
Enteral Arg-Gln Dipeptide Administration Increases Retinal Docosahexaenoic Acid and Neuroprotectin D1 in a Murine Model of Retinopathy of Prematurity.
Investigative ophthalmology & visual science.
59(2):858-869
[DOI] 10.1167/iovs.17-23034.
[PMID] 29490339.
2018
Enteral Feeding as an Adjunct to Hypothermia in Neonates with Hypoxic-Ischemic Encephalopathy.
Neonatology.
113(4):347-352
[DOI] 10.1159/000487848.
[PMID] 29510382.
2018
Food Protein-Induced Enterocolitis Instead of Necrotizing Enterocolitis? A Neonatal Intensive Care Unit Case Series.
The Journal of pediatrics.
200:270-273
[DOI] 10.1016/j.jpeds.2018.04.048.
[PMID] 29803301.
2018
Gastrointestinal Development: Implications for Management of Preterm and Term Infants.
Gastroenterology clinics of North America.
47(4):773-791
[DOI] 10.1016/j.gtc.2018.07.005.
[PMID] 30337032.
2018
Maternal milk feedings reduce sepsis, necrotizing enterocolitis and improve outcomes of premature infants.
Journal of perinatology : official journal of the California Perinatal Association.
38(1):71-74
[DOI] 10.1038/jp.2017.149.
[PMID] 29048409.
2018
Necrotizing enterocolitis comes in different forms: Historical perspectives and defining the disease.
Seminars in fetal & neonatal medicine.
23(6):370-373
[DOI] 10.1016/j.siny.2018.07.004.
[PMID] 30100524.
2018
Necrotizing enterocolitis.
Seminars in fetal & neonatal medicine.
23(6)
[DOI] 10.1016/j.siny.2018.08.009.
[PMID] 30279063.
2018
Necrotizing enterocolitis: The intestinal microbiome, metabolome and inflammatory mediators.
Seminars in fetal & neonatal medicine.
23(6):400-405
[DOI] 10.1016/j.siny.2018.08.001.
[PMID] 30172660.
2018
The Neonatal Microbiome and Its Partial Role in Mediating the Association between Birth by Cesarean Section and Adverse Pediatric Outcomes.
Neonatology.
114(2):103-111
[DOI] 10.1159/000487102.
[PMID] 29788027.
2017
Commensal Propionibacterium strain UF1 mitigates intestinal inflammation via Th17 cell regulation
The Journal Of Clinical Investigation.
127(11):3970-3986
[DOI] 10.1172/JCI95376.
[PMID] 28945202.
2017
Dysbiosis in the Neonatal Period: Role of Cesarean Section.
Nestle Nutrition Institute workshop series.
88:57-66
[DOI] 10.1159/000455215.
[PMID] 28346935.
2017
Epigenetic Matters: The Link between Early Nutrition, Microbiome, and Long-term Health Development.
Frontiers in pediatrics.
5
[DOI] 10.3389/fped.2017.00178.
[PMID] 28879172.
2017
Necrotizing Enterocolitis and Human Milk Feeding: A Systematic Review.
Clinics in perinatology.
44(1):49-67
[DOI] 10.1016/j.clp.2016.11.009.
[PMID] 28159209.
2017
Nutritional strategies and gut microbiota composition as risk factors for necrotizing enterocolitis in very-preterm infants.
The American journal of clinical nutrition.
106(3):821-830
[DOI] 10.3945/ajcn.117.152967.
[PMID] 28659297.
2017
Pathogenesis of NEC: Impact of an altered intestinal microbiome.
Seminars in perinatology.
41(1):29-35
[DOI] 10.1053/j.semperi.2016.09.015.
[PMID] 27986328.
2017
Personalization of the Microbiota of Donor Human Milk with Mother’s Own Milk.
Frontiers in microbiology.
8
[DOI] 10.3389/fmicb.2017.01470.
[PMID] 28824595.
2017
Post-hypoxia Invasion of the fetal brain by multidrug resistant Staphylococcus.
Scientific reports.
7(1)
[DOI] 10.1038/s41598-017-06789-6.
[PMID] 28743956.
2017
Potential Nutrients for Preventing or Treating Bronchopulmonary Dysplasia.
Paediatric respiratory reviews.
22:83-88
[DOI] 10.1016/j.prrv.2016.08.013.
[PMID] 27843119.
2017
Probiotics in Newborns and Children.
Pediatric clinics of North America.
64(6):1271-1289
[DOI] 10.1016/j.pcl.2017.08.006.
[PMID] 29173785.
2017
What Are Optimal Cesarean Section Rates in the U.S. and How Do We Get There? A Review of Evidence-Based Recommendations and Interventions.
Journal of women's health (2002).
26(12):1285-1291
[DOI] 10.1089/jwh.2016.6188.
[PMID] 28825512.
2016
Intestinal Microbiota Studies in Preterm Infants.
Journal of pediatric gastroenterology and nutrition.
62(2):193-4
[DOI] 10.1097/MPG.0000000000001068.
[PMID] 26655942.
2016
The human gut microbiota in perinatology and neonatology.
Seminars in fetal & neonatal medicine.
21(6)
[DOI] 10.1016/j.siny.2016.06.004.
[PMID] 27522308.
2016
The microbiome during pregnancy and early postnatal life.
Seminars in fetal & neonatal medicine.
21(6):373-379
[DOI] 10.1016/j.siny.2016.05.001.
[PMID] 27286643.
2016
Working group reports: evaluation of the evidence to support practice guidelines for nutritional care of preterm infants-the Pre-B Project.
The American journal of clinical nutrition.
103(2):648S-78S
[DOI] 10.3945/ajcn.115.117309.
[PMID] 26791182.
2015
Aspiration and evaluation of gastric residuals in the neonatal intensive care unit: state of the science.
The Journal of perinatal & neonatal nursing.
29(1):51-9; quiz E2
[DOI] 10.1097/JPN.0000000000000080.
[PMID] 25633400.
2015
Developmental aspects of maternal-fetal, and infant gut microbiota and implications for long-term health.
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1999
Necrotizing enterocolitis: pathophysiology and prevention.
JPEN. Journal of parenteral and enteral nutrition.
23(5 Suppl):S13-7
[PMID] 10483886.
1998
Enteral glutamine supplementation for very-low-birth-weight infants decreases hospital costs.
JPEN. Journal of parenteral and enteral nutrition.
22(6):352-6
[PMID] 9829607.
1997
Characterization of glutamine synthetase transcript, protein, and enzyme activity in the human placenta.
Placenta.
18(7):541-5
[PMID] 9290149.
1997
Enteral glutamine supplementation for very low birth weight infants decreases morbidity.
The Journal of pediatrics.
131(5):691-9
[PMID] 9403648.
1997
Glutamine metabolism in very low birth weight infants.
Pediatric research.
41(3):391-6
[PMID] 9078541.
1996
Characterization of glutaminase in the developing rat small intestine.
The Journal of nutrition.
126(4 Suppl):1121S-30S
[DOI] 10.1093/jn/126.suppl_4.1121S.
[PMID] 8642444.
1996
Enteral glutamine supplementation for the very low birthweight infant: plasma amino acid concentrations.
The Journal of nutrition.
126(4 Suppl):1115S-20S
[DOI] 10.1093/jn/126.suppl_4.1115S.
[PMID] 8642443.
1996
Glutamine nutrition and metabolism: where do we go from here ?
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
10(8):829-37
[PMID] 8666159.
1996
Necrotizing enterocolitis: the search for a unifying pathogenic theory leading to prevention.
Pediatric clinics of North America.
43(2):409-32
[PMID] 8614608.
1996
Nutrient absorption in the preterm neonate.
Clinics in perinatology.
23(2):229-43
[PMID] 8780903.
1996
Ontogeny of glutamine synthetase in rat small intestine.
Pediatric research.
39(4 Pt 1):643-8
[PMID] 8848339.
1995
Localization of rat small intestine glutamine synthetase using immunofluorescence and in situ hybridization.
JPEN. Journal of parenteral and enteral nutrition.
19(3):179-81
[PMID] 8551643.
1993
Meconium passage in very-low-birth-weight infants.
JPEN. Journal of parenteral and enteral nutrition.
17(6):537-40
[PMID] 8301808.
1993
Ontogeny of small intestinal glutaminase and glutamine synthetase in the rat: response to dexamethasone.
Biology of the neonate.
64(6):368-75
[PMID] 7904483.
1992
Gastrointestinal priming prior to full enteral nutrition in very low birth weight infants.
Journal of pediatric gastroenterology and nutrition.
15(2):163-70
[PMID] 1403464.
1992
The role of dietary cholesterol in infants.
Comprehensive therapy.
18(10):35-7
[PMID] 1458816.
1991
Effect of cholesterol deprivation on piglet small intestine and serum lipids.
Journal of pediatric gastroenterology and nutrition.
12(4):494-500
[PMID] 1865285.
1990
Ontogeny of prostaglandin E1 receptor binding in rat small intestine.
Prostaglandins, leukotrienes, and essential fatty acids.
41(1):63-6
[PMID] 2174566.
1990
Scientifically-based strategies for nutrition of the high-risk low birth weight infant.
European journal of pediatrics.
150(1):2-13
[PMID] 2127745.
1989
Changes in phospholipid and cholesterol concentrations of the rat microvillus membrane during maturation.
Journal of pediatric gastroenterology and nutrition.
9(1):89-93
[PMID] 2674384.
1989
Determination of extracellular fluid volume using impedance measurements.
Critical care medicine.
17(4):360-3
[PMID] 2702844.
1989
Factors associated with age of onset of necrotizing enterocolitis.
American journal of perinatology.
6(4):455-60
[PMID] 2789545.
1989
Functional development of the fetal gastrointestinal tract.
Seminars in perinatology.
13(3):224-35
[PMID] 2665101.
1989
Localization and characterization of prostaglandin E1 receptors in rat small intestine.
Prostaglandins, leukotrienes, and essential fatty acids.
36(3):129-34
[PMID] 2550964.
1988
Prostaglandin concentrations in human milk.
The American journal of clinical nutrition.
47(4):649-52
[PMID] 3162635.
1987
Alterations in piglet small intestine after cholesterol deprivation.
Pediatric research.
22(3):330-4
[PMID] 3116496.
Grants
Sep 2023
ACTIVE
Machine learning and Multiomics for Predictive Models and Biomarker Discovery in Preterm Infants
Role: Principal Investigator
Funding: BAYLOR COLLEGE OF MEDICINE
via NATL INST OF HLTH NICHD
Jul 2023
ACTIVE
Frequent Standardized Oral Care Using Human Milk to Reduce Oral Dysbiosis and Improve Health Outcomes in Preterm Very Low Birth Weight Infants
Role: Co-Investigator
Funding: GERBER FOUNDATION
Jan 2022
– Jan 2024
Human milk antibody response to COVID-19 vaccination and protection to breastfeeding infants
Role: Other
Funding: GERBER FOUNDATION
Dec 2019
– Dec 2024
A randomized, double blind, parallel-group, placebo controlled study to evaluate the efficacy and safety of IBP-9414 in premature infants 500-1500g birth weight in the prevention of necrotizing enterocolitis The Connection study
Role: Principal Investigator
Funding: INFANT BACTERIAL THERAPEUTICS AB
Aug 2018
– May 2023
Optimal Feeding Tube Dwell Time in VLBW to Reduce Feeding Tube Contamination
Role: Co-Investigator
Funding: NATL INST OF HLTH NINR
Dec 2016
– Nov 2019
Antibiotic Effects on the Developing Microbiome Metabolome and Morbidites in Preterm Neonates.
Role: Principal Investigator
Funding: NATL INST OF HLTH NICHD
Mar 2016
– Mar 2019
A RANDOMIZED DOUBLE BLIND PARALLEL GROUP DOSE ESCALATION PLACEBO CONTROLLED MULTICENTER STUDY TO INVESTIGATE THE…..
Role: Principal Investigator
Funding: PREMIER RESEARCH INTERNATIONAL
via INFANT BACTERIAL THERAPEUTICS AB
Oct 2015
ACTIVE
Coordinating Investigator Clinical Trial IBP-9414 and clinical expert services
Role: Principal Investigator
Funding: INFANT BACTERIAL THERAPEUTICS AB
Sep 2015
– Sep 2018
Refaunation of Donor Human Milk with Mother's Own Milk
Role: Principal Investigator
Funding: MEDELA AG
Mar 2013
– Jan 2018
Routine Aspiration of Residual Gastric Contents in Very Low Birth Weight Infants
Role: Project Manager
Funding: NATL INST OF HLTH NINR
Education
Fellowship – Neonatal – Perinatal Medicine
1980
·
Stanford University
Residency – Pediatrics
1978
·
John's Hopkins University
Medical Degree
1975
·
University of Wisconsin
Contact Details
Phones:
- Business:
- (352) 273-8985
Emails:
- Business:
- neu@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100296
GAINESVILLE FL 32610 - Business Street:
-
HD 112 JHMHC
GAINESVILLE FL 32611